Relaxed multi category structure of a global category of rings and modules

In this paper we describe how to give a particular global category of rings and modules the structure of a relaxed multi category, and we describe an algebra in this relaxed multi category such that vertex algebras appear as such algebras.Comment: 19 pages, xy-pic, epsfig. Updated version to appear in the Journal of Pure and Applied Algebra including various corrections and additional citation

Sequence-Based Mapping and Genome Editing Reveal Mutations in Stickleback Hps5 Cause Oculocutaneous Albinism and the casper Phenotype.

Here, we present and characterize the spontaneous X-linked recessive mutation casper, which causes oculocutaneous albinism in threespine sticklebacks (Gasterosteus aculeatus). In humans, Hermansky-Pudlak syndrome results in pigmentation defects due to disrupted formation of the melanin-containing lysosomal-related organelle (LRO), the melanosome. casper mutants display not only reduced pigmentation of melanosomes in melanophores, but also reductions in the iridescent silver color from iridophores, while the yellow pigmentation from xanthophores appears unaffected. We mapped casper using high-throughput sequencing of genomic DNA from bulked casper mutants to a region of the stickleback X chromosome (chromosome 19) near the stickleback ortholog of Hermansky-Pudlak syndrome 5 (Hps5). casper mutants have an insertion of a single nucleotide in the sixth exon of Hps5, predicted to generate an early frameshift. Genome editing using CRISPR/Cas9 induced lesions in Hps5 and phenocopied the casper mutation. Injecting single or paired Hps5 guide RNAs revealed higher incidences of genomic deletions from paired guide RNAs compared to single gRNAs. Stickleback Hps5 provides a genetic system where a hemizygous locus in XY males and a diploid locus in XX females can be used to generate an easily scored visible phenotype, facilitating quantitative studies of different genome editing approaches. Lastly, we show the ability to better visualize patterns of fluorescent transgenic reporters in Hps5 mutant fish. Thus, Hps5 mutations present an opportunity to study pigmented LROs in the emerging stickleback model system, as well as a tool to aid in assaying genome editing and visualizing enhancer activity in transgenic fish

A Case Report of Folie\u27a Deux: Husband-and-Wife

Shared paranoid disorder is a relatively rare psychiatric disorder in which paranoid delusions are transferred from one individual to one or more other susceptible person(s) in close association. Folie a deux describes a shared paranoid disorder involving two people and is characterized by a complex dependant relationship between the involved individuals. Provided there is no additional underlying psychopathology, there is a good prognosis for the submissive partner. Here we present a case report and discussion off folie a deux involving a husband and wife. Although folie a deux is a relatively uncommon disorder, it is important to recognize such cases due to the potential for recovery in the submissive partner

Modeling the environmental controls on tree water use at different temporal scales

Acknowledgements This study is part of the first author’s PhD projects in 2010–2014, co-funded by the National Centre for Groundwater Research and Training in Australia and the China Scholarship Council. We give thanks to Zijuan Deng and Xiang Xu for their assistance in the field. Constructive comments and suggestion from the anonymous reviewers are appreciated for significant improvement of the manuscript.Peer reviewedPostprin

Multiband radar characterization of forest biomes

The utility of airborne and orbital SAR in classification, assessment, and monitoring of forest biomes is investigated through analysis of orbital synthetic aperature radar (SAR) and multifrequency and multipolarized airborne SAR imagery relying on image tone and texture. Preliminary airborne SAR experiments and truck-mounted scatterometer observations demonstrated that the three dimensional structural complexity of a forest, and the various scales of temporal dynamics in the microwave dielectric properties of both trees and the underlying substrate would severely limit empirical or semi-empirical approaches. As a consequence, it became necessary to develop a more profound understanding of the electromagnetic properties of a forest scene and their temporal dynamics through controlled experimentation coupled with theoretical development and verification. The concatenation of various models into a physically-based composite model treating the entire forest scene became the major objective of the study as this is the key to development of a series of robust retrieval algorithms for forest biophysical properties. In order to verify the performance of the component elements of the composite model, a series of controlled laboratory and field experiments were undertaken to: (1) develop techniques to measure the microwave dielectric properties of vegetation; (2) relate the microwave dielectric properties of vegetation to more readily measured characteristics such as density and moisture content; (3) calculate the radar cross-section of leaves, and cylinders; (4) improve backscatter models for rough surfaces; and (5) relate attenuation and phase delays during propagation through canopies to canopy properties. These modeling efforts, as validated by the measurements, were incorporated within a larger model known as the Michigan Microwave Canopy Scattering (MIMICS) Model

SIR-B measurements and modeling of vegetation

A summary is presented of the results derived from analysis of six SIR-B data takes over an agricultural test site in west central Illinois. The first part describes the procedure used to calibrate the SIR-B imagery, the second part pertains to the observed radar response to soil moisture content, and the last part examines the information derivable from multiangle observations

Measurement of Quantum Fluctuations in Geometry

A particular form for the quantum indeterminacy of relative spacetime position of events is derived from the limits of measurement possible with Planck wavelength radiation. The indeterminacy predicts fluctuations from a classically defined geometry in the form of ``holographic noise'' whose spatial character, absolute normalization, and spectrum are predicted with no parameters. The noise has a distinctive transverse spatial shear signature, and a flat power spectral density given by the Planck time. An interferometer signal displays noise due to the uncertainty of relative positions of reflection events. The noise corresponds to an accumulation of phase offset with time that mimics a random walk of those optical elements that change the orientation of a wavefront. It only appears in measurements that compare transverse positions, and does not appear at all in purely radial position measurements. A lower bound on holographic noise follows from a covariant upper bound on gravitational entropy. The predicted holographic noise spectrum is estimated to be comparable to measured noise in the currently operating interferometer GEO600. Because of its transverse character, holographic noise is reduced relative to gravitational wave effects in other interferometer designs, such as LIGO, where beam power is much less in the beamsplitter than in the arms.Comment: 7 pages, 2 figures, LaTeX. Extensive rewrite of original version, including more detailed analysis. Main result is the same but the estimate of noise in strain units for GEO600, showing 1/f behavior at low f and flat at high f, is improved. To appear in Phys. Rev.